HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → 1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 6-Chloronaphthalene-2-sulfonyl chloride | HCID 10635129 | — |
| Product | 1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride | HCID 22709766 | 58% |
Reaction Steps
Using analogous procedures to those described in two of the paragraphs of the portion of Example 50 which is concerned with the preparation of starting materials, 1-tert-butoxycarbonylpiperazine was reacted with 6-chloronaphth-2-ylsulphonyl chloride to give 1-(6-chloronaphth-2-ylsulphonyl)piperazine hydrochloride salt in 58% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730672B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-e18522bccacf4f38a5754bdb2786351f |
| Source note | uspto-grants-2004_05 |