HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Pyridinyl)-4-piperidinecarbonyl chloride → 4-(2-Naphthylsulphonyl)-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Pyridinyl)-4-piperidinecarbonyl chloride | HCID 11183700 | — |
| Reactant | 4-(2-Naphthylsulfonyl)piperidine | HCID 22721937 | — |
| Product | 4-(2-Naphthylsulphonyl)-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperidine | HCID 22721958 | 33% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 1-(4-pyridyl)piperidine-4-carbonyl chloride was reacted with 4-(2-naphthylsulphonyl)piperidine to give 4-(2-naphthylsulphonyl)-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperidine in 33% yield;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730672B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-171880757bf04851a00a5e24b8a4a97b |
| Source note | uspto-grants-2004_05 |