4'-Bromobiphenyl-4-sulfonyl chloride → HCID 22721817, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 89, 4-[4-(4-pyridyl)piperazin-1-ylcarbonyl]aniline was reacted with 4′-bromo-4-biphenylylsulphonyl chloride to give N-{4-[4-(4-pyridyl)-piperazin-1-ylcarbonyl]phenyl}-4′-bromo-4-biphenylylsulphonamide hydrochloride salt in 90% yield, m.p. 201-205° C.;

Provenance & Evidence