HCID 178527380, compound → HCID 22722071, compound

HRID 1581641Notes

Reaction equation

HRID 1581641 reaction equation
[CH:1]1([N:6]2[C:10]([C:11]3[CH:16]=[CH:15][NH:14][C:13](=S(=O)=O)[N:12]=3)=[C:9]([C:20]3[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=3)[N:8]=[CH:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:27]1([N:33]2C(C3C=CNC(=S(=O)=O)N=3)=C(C3C=CC(F)=CC=3)N=C2)[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1>>[CH:1]1([N:6]2[C:10]([C:11]3[CH:16]=[CH:15][N:14]=[C:13]([NH:33][C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[N:12]=3)=[C:9]([C:20]3[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=3)[N:8]=[CH:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 178527380HCID 178527380, compoundHCID 178527381HCID 178527381, compound

Product 1

HCID 22722071HCID 22722071, compound

Procedure

The reaction was conducted in a manner analogous to Example 2d except substituting polymer-bound 1-cyclopentyl-4-(4-fluorophenyl)-5-[(2-sulfonyl)pyrimidin-4-yl]imidazole for polymer-bound 1-cyclohexyl-4-(4-fluorophenyl)-5-[(2-sulfonyl)pyrimidin-4-yl]imidazole: ESMS m/z=400 (MH)+

Sources & evidence

ORD record
ord-fb3383dd332b44d382357e7417f9f944
Source dataset
uspto-grants-2004_05
Patent number
US06730683B2

Reaction notes

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