HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 10155070, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 5-Methoxycarbonylamino-N-acetyltryptamine | HCID 4284525 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Chloroform methanol | HCID 21584188 | — |
| Product | HCID 10155070 | HCID 10155070 | — |
Reaction Steps
A solution of 5-methoxycarbonylamino-N-acetyltryptamine (0.05 mmol) in acetic acid (0.5 mL) is treated with N-bromosuccinimide (0.05 mmol) 3.5 h at 25° C. The solution is next neutralized with 50% sodium hydroxide solution and extracted with ethyl acetate. The organic extract is evaporated and the purified product obtained following chromatography on silica gel with 2% methanol-chloroform as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730707B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-8d4a595a209e43b882432c6ad92f9866 |
| Source note | uspto-grants-2004_05 |