HCID 10881632, compound → HCID 12994078, compound

HRID 1581760Notes

Reaction equation

HRID 1581760 reaction equation
[CH:1]([C@@:4]12[CH2:9][C@@H:8]1[C@H:7]([CH3:10])[C@@H:6]([C:11]1[CH:24]=[CH:23][C:22]3[C:13](=[C:14]4[C:19](=[CH:20][CH:21]=3)[CH:18]=[CH:17][CH:16]=[N:15]4)[N:12]=1)[CH2:5]2)([CH3:3])[CH3:2].[I-].[I-].[Sm+2].[CH3:28][C@@H:29]1[C:34](=[O:35])[CH2:33][C@:32]2([CH:36]([CH3:38])[CH3:37])[C@H:30]1[CH2:31]2>>[CH:1]([C@@:4]12[CH2:9][C@@H:8]1[C@H:7]([CH3:10])[C@@H:6]([C:11]1[CH:24]=[CH:23][C:22]3[C:13](=[C:14]4[C:19](=[CH:20][CH:21]=3)[CH:18]=[CH:17][C:16]([C@:34]3([OH:35])[C@@H:29]([CH3:28])[C@@H:30]5[C@@:32]([CH:36]([CH3:38])[CH3:37])([CH2:31]5)[CH2:33]3)=[N:15]4)[N:12]=1)[CH2:5]2)([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 10881632HCID 10881632, compoundHCID 12304612HCID 12304612, compoundHCID 178506586HCID 178506586, compound

Product 1

HCID 12994078HCID 12994078, compound

Procedure

By following General Procedure I, 2-((1S,3S,4S,5R)-(1-isopropyl-4-methylbicyclo[3.1.0]hex-3-yl))-1,10-phenanthroline prepared as described by Example 18, is reacted with samarium diiodide and (−)-thujone to form the title compound.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-fdac7e4183cf4856937d57b8fa6ec827
Source dataset
uspto-grants-2004_05
Patent number
US06730788B1

Reaction notes

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