HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophene-3-boronic acid → 2-Fluoro-6-(thien-3-yl)anisole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophene-3-boronic acid | HCID 581760 | — |
| Reactant | 1-Fluoro-3-iodo-2-methoxybenzene | HCID 22723433 | — |
| Product | 2-Fluoro-6-(thien-3-yl)anisole | HCID 22723449 | — |
Reaction Steps
2-Fluoro-6-(thien-3-yl)anisole is prepared from 2-fluoro-6-iodoanisole (1.35 g, 5.36 mmol) by Suzuki coupling with thiophene-3-boronic acid according to the general procedure described in Representative Procedure 4(b) below; yield: 1.05 g (94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06730792B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-81b858b0e9e14c4fa05fb37afa943ecf |
| Source note | uspto-grants-2004_05 |