Glycerol → HCID 178512162, compound

HRID 1581898Notes

Reaction equation

HRID 1581898 reaction equation
[OH:1][CH2:2][CH:3]([CH2:5][OH:6])[OH:4].[CH:7]1[C:12]([NH:13][C:14]([NH:16][C:17]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][NH:26][C:27]([NH:29][C:30]([NH:32][C:33]2[CH:34]=[CH:35][C:36]([Cl:39])=[CH:37][CH:38]=2)=[NH:31])=[NH:28])=[NH:18])=[NH:15])=[CH:11][CH:10]=[C:9]([Cl:40])[CH:8]=1.[CH2:41]([OH:53])[C@@H:42]([OH:52])[C@@H:43]([OH:51])[C@H:44]([OH:50])[C@@H:45]([OH:49])[C:46]([OH:48])=[O:47]>O>[OH:1][CH2:2][CH:3]([CH2:5][OH:6])[OH:4].[CH:34]1[C:33]([NH:32][C:30]([NH:29][C:27]([NH:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][NH:19][C:17]([NH:16][C:14]([NH:13][C:12]2[CH:7]=[CH:8][C:9]([Cl:40])=[CH:10][CH:11]=2)=[NH:15])=[NH:18])=[NH:28])=[NH:31])=[CH:38][CH:37]=[C:36]([Cl:39])[CH:35]=1.[CH2:41]([OH:53])[C@@H:42]([OH:52])[C@@H:43]([OH:51])[C@H:44]([OH:50])[C@@H:45]([OH:49])[C:46]([OH:48])=[O:47]

Participants

4

Reactant 2

HCID 753GlycerolHCID 178512161HCID 178512161, compound

Product 1

HCID 178512162HCID 178512162, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A stock solution of 2/1 glycerin/chlorhexidine gluconate (CHG) was prepared by dissolving 2 parts of glycerin (Aldrich Chemical Company, Milwaukee, Wis.) in 5 parts of 20 wt. % CHG in water (Medichem S. A., Barcelona, Spain). The water from this solution was removed under vacuum and at 60° C. using a Rotavapor R110 (Buchi, Germany).

Workup

  1. customThe water from this solution was removed under vacuum and at 60° C.

Sources & evidence

ORD record
ord-c7bc4ebca15a48f4bb4b2fdb02cd7536
Source dataset
uspto-grants-2004_05
Patent number
US06733745B2

Reaction notes

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