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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1581973Generated: October 30, 2026

2-Aminoindane → 2-(2-Indanylamino)-1-thia-2,3,5,7-tetraazaindene

https://huagongshe.com/reaction/1581973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminoindaneHCID 76310—
Reactant2-Chloro-1-thia-2,3,5,7-tetraazaindeneHCID 22719619—
Product2-(2-Indanylamino)-1-thia-2,3,5,7-tetraazaindeneHCID 2271963951.7%

Reaction Steps

Using 2-chloro-1-thia-2,3,5,7-tetraazaindene (50 mg, 0.29 mmol) (see J. Org. Chem. 26, 4961 (1961), J. Chem. Soc. (C) 1856 (1967)) and 2-aminoindan (120 mg, 0.90 mmol), a similar procedure to Example 1 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=3:1) to obtain the title compound (41 mg, 0.15 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06734180B1
Source datasetuspto-grants-2004_05
ORD IDord-25cc741cf97641a29c3d3bb813457fe9
Source noteuspto-grants-2004_05