2-Aminoindane → 4-(2-Indanylamino)-5-(2-thienyl)thieno[2,3-d]pyrimidine

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Reaction Steps

Using 4-chloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (50 mg, 0.20 mmol) and 2-aminoindan (110 mg, 0.80 mmol), a similar procedure to Example 1 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=1:1) to obtain the title compound (70 mg, 0.20 mmol) having the following physical properties:

Provenance & Evidence