HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → N-[4-Methoxy-7-(tetrahydro-pyran-2-yl)-benzothiazol-2-yl]-2-morpholin-4-yl-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-bromo-N-[4-methoxy-7-(tetrahydro-pyran-2-yl)-benzothiazol-2-yl]-isonicotinamide | HCID 10310452 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | N-[4-Methoxy-7-(tetrahydro-pyran-2-yl)-benzothiazol-2-yl]-2-morpholin-4-yl-isonicotinamide | HCID 10288409 | — |
Reaction Steps
From 2-bromo-N-[4-methoxy-7-(tetrahydro-pyran-2-yl)-benzothiazol-2-yl]-isonicotinamide with cesium carbonate and morpholine in NMP. ES-MS m/e (%): 455 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06734179B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-4eddccf2b1334718a5a2eac8dd276d5c |
| Source note | uspto-grants-2004_05 |