1-Bromoheptane → HCID 22718708, compound

HRID 1582624Notes

Reaction equation

HRID 1582624 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([C:9]([OH:17])([CH3:16])[CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)[CH:3]=1.[CH2:18](Br)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])=[C:4]([C:9]([OH:17])([CH3:16])[CH2:10][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)[CH:3]=1

Participants

3

Reactant 2

HCID 123691-BromoheptaneHCID 12972900HCID 12972900, compound2×

Product 1

HCID 22718708HCID 22718708, compoundYield 94.3%

Procedure

The general procedure of Example 6 was repeated using 4-fluoro-2-(1-hydroxy-2-(1H-1-imidazolyl)-1-methylethyl)phenol [compound (2-4)] and n-heptyl bromide, to thereby yield 2-(5-fluoro-2-(n-heptyloxy)phenyl)-1-(1H-1-imidazolyl)-2-propanol as colorless crystals (yield: 94.3%).

Sources & evidence

ORD record
ord-7806b1dca95248b0bd73bee95e263333
Source dataset
uspto-grants-2004_05
Patent number
US06737434B2

Reaction notes

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