HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1582638Generated: November 3, 2026
Benzaldehyde, 2-fluoro-3-(phenylmethoxy)- → HCID 54429135, compound
https://huagongshe.com/reaction/1582638
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzaldehyde, 2-fluoro-3-(phenylmethoxy)- | HCID 561331 | — |
| Reactant | Methyl 2-azidoacetate | HCID 4020482 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54429135 | HCID 54429135 | — |
Reaction Steps
A mixture of methylazidoacetate (36.64 g) and 2-Fluoro-3-benzyloxy benzaldehyde (18.32 g) in methanol (250 ml) was added dropwise, with stirring, over 1 hour to a mixture of sodium methoxide (17.20 g) in methanol (100 ml) at −25° C. under a stream of argon. Mixture was left to stir for 20 minutes, allowed to warm to 5° C. and stirred overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06737435B1 |
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| Source dataset | uspto-grants-2004_05 |
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| ORD ID | ord-5685a2cfb0cb4f22b1cebcb5e578605e |
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| Source note | uspto-grants-2004_05 |
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