HCID 22718742, compound → HCID 22718724, compound

Participants

Reaction Steps

5% Pd/C (100 mg) was added to a stirred solution of ethyl-N-(3,4-dichlorobenzyl)3-methoxy-5-benzyloxyindole-2-carboxylate (0.9 g) in ethyl acetate (50 ml) and the mixture was hydrogenated for 12 hours. Catalyst filtered off and filtrate evaporated to give a brown oil (0.61 g) which was used without further purification. NMR: δ 1.4 (t, 3H), 4.0 (s, 3H), 4.4 (q, 2H), 5.6 (s, 2H), 6.8 (dd, 1H), 6.9 (dd, 1H), 7.1 (m, 3H), 7.3 (d,1H); m/z 394 (MH+)

Provenance & Evidence