HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate → 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate | HCID 12048018 | — |
| Reactant | 3-Methoxy-7alpha-(2-propenyl)estra-1,3,5(10)-trien-17beta-ol | HCID 69414807 | — |
| Product | 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid | HCID 53318530 | — |
Reaction Steps
Starting with the 3-methoxy-7α-(2-propenyl)estra-1,3,5(10)-trien-17β-ol prepared in Example 13 and ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate prepared separately, the same procedure as shown in Example 13 was repeated to give 10-[3,17β-dihydroxyestra-1,3,5(10)-trien-7α-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06737417B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-8af89f346de045ffa6b99b0b79a761ca |
| Source note | uspto-grants-2004_05 |