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Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoate → 10-(3,17beta-Dihydroxyestra-1,3,5(10)-trien-11beta-yl)-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoate | HCID 12043782 | — |
| 反応物 | 3,17beta-Bis(benzyloxy)-11-(2-propenyl)estra-1,3,5(10),9(11)-tetraene | HCID 69413225 | — |
| 生成物 | 10-(3,17beta-Dihydroxyestra-1,3,5(10)-trien-11beta-yl)-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid | HCID 86588534 | — |
反応手順
Starting with the 3,17β-bis(benzyloxy)-11-(2-propenyl)estra-1,3,5(10), 9(11)-tetraene prepared in Example 20 and ethyl 2-(4,4,5,5,5-pentafluoro-pentyl)-8-nonenoate prepared separately, the same procedure as shown in Example 20 was repeated to give 10-(3,17β-dihydroxyestra-1,3,5(10)-trien-11β-yl)-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06737417B2 |
| 出典データセット | uspto-grants-2004_05 |
| ORD ID | ord-9ff9539ce2de4fdd98db4e9ddc1dd49d |
| 出典メモ | uspto-grants-2004_05 |