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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1582831Generated: November 2, 2026

Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoate → 11-(3,17beta-Dihydroxyestra-1,3,5(10)-trien-11beta-yl)-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acid

https://huagongshe.com/reaction/1582831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoateHCID 12043786—
Reactant3,17beta-Bis(benzyloxy)-11-(2-propenyl)estra-1,3,5(10),9(11)-tetraeneHCID 69413225—
Product11-(3,17beta-Dihydroxyestra-1,3,5(10)-trien-11beta-yl)-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acidHCID 86588535—

Reaction Steps

Starting with the 3,17β-bis(benzyloxy)-11-(2-propenyl)estra-1,3,5(10), 9(11)-tetraene prepared in Example 20 and ethyl 2-(4,4,5,5,5-pentafluoro-pentyl)-9-decenoate prepared separately, the same procedure as shown in Example 20 was repeated to give 11-(3,17β-dihydroxyestra-1,3,5(10)-trien-11β-yl)-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06737417B2
Source datasetuspto-grants-2004_05
ORD IDord-359914839fd342cfa01ac875c07c00e9
Source noteuspto-grants-2004_05