Thionyl Chloride → HCID 22715656, compound

HRID 1582935Notes

Reaction equation

HRID 1582935 reaction equation
O[CH2:2][CH2:3][N:4]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)=[N:5]1.O=S(Cl)[Cl:17]>>[Cl:17][CH2:2][CH2:3][N:4]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)=[N:5]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 227156972-[3-(Pyridin-4-yl)-1H-pyrazol-1-yl]ethan-1-ol

Product 1

HCID 22715656HCID 22715656, compound

Procedure

C] 1-(2-Chloroethyl)-3-(4-pyridinyl)-1H-pyrazole was prepared according to example 14C from 1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazole by treatment with SOCl2. MS (EI): 207.1 (M+). 1H-NMR (DMSO-d6): 4,06 (t, 2H), 4.53 (t, 2H), 6.92 (d, 1H), 7.76 (m, 2H), 7.93 (d, 1H), 8.58 (m, 2H).

Sources & evidence

ORD record
ord-6c8be01f6e754923850bc17fc228add8
Source dataset
uspto-grants-2004_05
Patent number
US06740642B2

Reaction notes

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