Methyl iodide → HCID 22716711, compound

Participants

Reaction Conditions

Reaction Steps

Glutaric anhydride and 6-chloro-3-(3-chlorobenzoyl)-2-ethylaminopyridine were reacted under heating at 150° C. and then worked up in a usual manner. The resulting compound was reacted with methyl iodide in 2-butanone in the presence of potassium carbonate at 60° C. Thereafter, the reaction mixture was worked up and purified in a usual manner to obtain methyl 3-[7-chloro-4-(3-chlorophenyl)-1-ethyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]propanoate as a colorless solid. MS: 405.

Provenance & Evidence