Tetrahydrofuran → HCID 22716661, compound

Participants

Reaction Steps

To a THF solution of 4-(3-chlorophenyl)-1-ethyl-3-(3-hydroxypropyl)-7-methyl-1,8-naphthyridin-2(1H)-one were added triethylamine and methanesulfonyl chloride, followed by reaction under heating. Thereafter, the reaction mixture was worked up and purified in a usual manner to obtain 4-(3-chlorophenyl)-1-ethyl-3(3-methanesulfonyloxypropyl)-7-methyl-1,8-naphthyridin-2(1H)-one. NMR1: 4.67 (2H, q, J=7.1 Hz), 4.18 (2H, t, J=6.3 Hz), 2.93 (3H, s).

Provenance & Evidence