Sodium borohydride → HCID 22716657, compound

Participants

Reaction Steps

To an ethanol solution of ethyl 1-[4-(3-chlorophenyl)-1-ethyl-7-formyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]piperidine-4-carboxylate was added sodium borohydride under ice cooling, followed by stirring for 15 minutes. Thereafter, the reaction mixture was worked up and purified in a usual manner to obtain ethyl 1-[4-(3-chlorophenyl)-1-ethyl-7-hydroxymethyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]piperidine-4-carboxylate as a yellow oily substance. MS: 470.

Provenance & Evidence