Hydrochloric Acid → HCID 69711290, compound

Participants

Reaction Conditions

Reaction Steps

To 370 mg of ethyl {4-[4-(3-bromophenyl)-1-ethyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]piperidin-1-yl}acetate was added 5 ml of 6M hydrochloric acid, followed by stirring at 100° C. for 15 hours. After removal of the solvent, the resulting crude crystals were recrystallized from ethanol-acetonitrile to obtain 185 mg of {4-[4-(3-bromophenyl)-1-ethyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]piperidin-1-yl}acetic acid monohydrochloride as colorless crystals.

Provenance & Evidence