2-(2,4-Difluorobenzyloxy)-5-formylbenzoic acid → n,n-Di-n-pentyl-2-(2,4-difluorobenzyloxy)-5-formylbenzamide

Participants

Reaction Steps

N,N-Di-n-pentyl-2-(2,4-difluorobenzyloxy)-5-formylbenzamide was prepared from 2-(2,4-difluorobenzyloxy)-5-formylbenzoic acid (200 mg, 1 eq) using the same procedure as for N,N-di-n-pentyl-2-methoxy-5-formylbenzamide. The product was obtained as a pale brown oil (442 mg, 99%). 1H NMR (CDCl3) δ9.89 (s, 1H, O═C—H), 5.22 (d, 1H, CH2Ar), 5.10 (d, 1H, CH2Ar), 3.74 (m, 1H, NCH2), 3.14 (m, 1H, NCH2), 3.05 (m, 2H, NCH2).

Provenance & Evidence