HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Toluidine → HCID 178428815, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Product | HCID 178428815 | HCID 178428815 | 38% |
Reaction Steps
Following a procedure similar to (454a), 2-methylaniline (21.4 g, 0.2 mol) was condensed with methyl acetoacetate (23.2 g, 0.2 mol) to provide the desired 2,8-dimethyl-4-hydroxyquinoline (456a) (13.0 g, 38%). MS (AP+): 173 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740649B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-d9fd9494313348f19c446c570f40ba5c |
| Source note | uspto-grants-2004_05 |