HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54052129, compound → Miridesap
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54052129 | HCID 54052129 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Miridesap | HCID 125516 | 59.5% |
Reaction Steps
410 mg (0.79 mmol) (R)-1-[6-[(R)-2-benzyloxycarbonyl-pyrrolidin-1-yl]-6-oxo-hexanoyl]-pyrrolidine-2-carboxylic acid benzyl ester in 100 ml methanol were hydrogenated in the presence of 50 mg 5% Pd on carbon. Filtration and evaporation of the solvent yielded 160 mg (59%) (R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]-pyrrolidine-2-carboxylic acid as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740760B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-194467bfb2d744c3b2038485c4564c1f |
| Source note | uspto-grants-2004_05 |