HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride → HCID 178525081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Reactant | HCID 178418675 | HCID 178418675 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178525081 | HCID 178525081 | 91% |
Reaction Steps
Using General Procedure A with 2.0 g (8.2 mmol) D-Proline benzyl ester hydrochloride and 700 mg (4.1 mmol) cis-cyclohexane-1,4-dicarboxylic acid afforded, after flash chromatography (EtOAc), 2.0 g (91%) of the title compound as a colorless oil. MS m/e (%): 547 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740760B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-cc61973ba41549f08593c925e9544827 |
| Source note | uspto-grants-2004_05 |