HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Pyridinedicarboxylic acid → HCID 54082754, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Pyridinedicarboxylic acid | HCID 10367 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 54082754 | HCID 54082754 | 77% |
Reaction Steps
Using General Procedure A with 5.8 g (24.0 mmol) D-Proline benzyl ester hydrochloride and 2.0 g (12.0 mmol) pyridine-2,6-dicarboxylic acid afforded, after flash chromatography (EtOAc), 5.0 g (77%) of the title compound as a yellow oil. MS m/e (%): 559 (M+NH4+, 60), 542 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06740760B2 |
| Source dataset | uspto-grants-2004_05 |
| ORD ID | ord-357a4916ec7645198c562d136a17de50 |
| Source note | uspto-grants-2004_05 |