HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl oxoacetate → Ethyl 5-butyl-1,3-dioxane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl oxoacetate | HCID 70211 | — |
| Reactant | 2-n-Butylpropane-1,3-diol | HCID 2795259 | — |
| Product | Ethyl 5-butyl-1,3-dioxane-2-carboxylate | HCID 20260037 | — |
Reaction Steps
2-(3,5-Difluoro-4-cyanophenyl)-5-butyl-1,3-dioxane is obtained analogously to Example 1 using 5-butyl-1,3-dioxane-2-carboxylic acid chloride (obtainable by reacting ethyl glyoxylate with 2-butylpropane-1,3-diol to give ethyl 5-butyl-1,3-dioxane-2-carboxylate, saponifying the latter and reacting the resulting free acid with SOCl2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04551264 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-d81e8c40986d4cae80c758061a900c7b |
| Source note | uspto-grants-1985_11 |