3-Methyl-2-nitrobenzoic acid → 2-Amino-3-methylbenzoic acid

Participants

Reaction Steps

A solution of 3-methyl-2-nitrobenzoic acid (7 g) in ethanol (250 ml) was reduced with hydrogen gas at 2 psi over 5% palladium/carbon (0.7 g) catalyst. After hydrogen uptake ceased, the mixture was filtered and solvent removed by a rotary evaporator to give a white solid. Purification was by recrystallization from ethyl ether-hexane, m.p. ca. 170°-173° C.

Provenance & Evidence