Benzyl chloromethyl ether → HCID 18600036, compound

HRID 1583259Notes

Reaction equation

HRID 1583259 reaction equation
[N+:1]([C:3](=[C:14]1[CH2:19][CH2:18][C@H:17]2[C@H:20]3[C@H:30]([CH2:31][CH2:32][C@:15]12[CH3:16])[C@:28]1([CH3:29])[C:23](=[CH:24][C:25](=[O:33])[CH:26]=[CH:27]1)[CH2:22][CH2:21]3)[S:4]([C:7]1[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][CH:8]=1)(=[O:6])=[O:5])#[C-:2].Cl[CH2:35][O:36][CH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[N+:1]([C:3]([S:4]([C:7]1[CH:8]=[CH:9][C:10]([CH3:13])=[CH:11][CH:12]=1)(=[O:6])=[O:5])([C:14]1[C@:15]2([CH3:16])[C@H:17]([C@H:20]3[C@H:30]([CH2:31][CH2:32]2)[C@:28]2([CH3:29])[C:23](=[CH:24][C:25](=[O:33])[CH:26]=[CH:27]2)[CH2:22][CH2:21]3)[CH2:18][CH:19]=1)[CH2:35][O:36][CH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)#[C-:2]

Participants

3

Reactant 2

HCID 137983Benzyl chloromethyl etherHCID 56609061HCID 56609061, compound

Product 1

HCID 18600036HCID 18600036, compound

Procedure

The title compound was prepared according to the method described in Example 8a, starting from 17-(isocyano-p-methylphenylsulfonylmethylene)-androsta-1,4-diene-3-one (462 mg, 1 mmol). Yield: 625 mg of a mixture of the title compound and chloromethyl benzylether (1:1).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-db7def74a64d4328866a405d6bc376e3
Source dataset
uspto-grants-1985_11
Patent number
US04551278

Reaction notes

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