Dichloromethane → HCID 18600043, compound

Participants

Reaction Steps

3-Methoxy-17-(isocyano-p-methylphenylsulfonylmethylene)-androsta-3,5,9(11)-triene (476 mg, 1.00 mmol) and triethylbenzylammonium chloride (20 mg) were dissolved in methylene chloride (10 ml). After stirring for 2 hours at 25° C. with a sodium hydroxide solution (5 ml, 50%), the organic layer was seperated and dried over Na2SO4, followed by filtration over alumina (act. II-III). Evaporation of the solvent afforded the title compound (368 mg, 70%).

Provenance & Evidence