HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Bromo-1,1,2-trifluoroethoxy)-4-nitrobenzene → 4-(2-Bromo-1,1,2-trifluoroethoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Bromo-1,1,2-trifluoroethoxy)-4-nitrobenzene | HCID 13228495 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(2-Bromo-1,1,2-trifluoroethoxy)aniline | HCID 13228496 | 101.4% |
Reaction Steps
700 ml of absolute ethyl acetate were added to 275 g of 4-(2-bromo-1,1,2-trifluoroethoxy)-nitrobenzene, and hydrogenation was carried out using 20 g of palladium on active carbon. The catalyst was filtered off and the solvent was removed. 251 g of the compound were obtained; this was pure according to NMR analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04551448 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-22a28a64e3884d7dbf9b27b8bea3d974 |
| Source note | uspto-grants-1985_11 |