HCID 131714405, compound → HCID 71738033, compound

HRID 1583387Notes

Reaction equation

HRID 1583387 reaction equation
[Na].[N:2]1[C:11](=[O:12])[C:10]2[C:6]([N:7]=[CH:8][N+:9]=2[O-:13])=[N:5][C:3]=1[NH2:4]>C(O)(=O)C>[N:2]1[C:11](=[O:12])[C:10]2[C:6]([N:7]=[CH:8][N+:9]=2[O-:13])=[N:5][C:3]=1[NH2:4]

Participants

3

Reactant 1

HCID 131714405HCID 131714405, compound

Product 1

HCID 71738033HCID 71738033, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To 60 ml of a solution containing approximately 450 mg of guanine-N7 -oxide sodium salt was added 1.0M acetic acid to pH 7.9. The white precipitate that formed was collected and dried to yield 276 mg partially crystalline neutral guanine-N7 -oxide. Additional 1.0M acetic acid was added to the mother liquor to a final pH of 5.9. After standing overnight at 5° C., an additional 46 mg of neutral guanine-N7 -oxide precipitated as a white crystalline solid.

Workup

  1. customThe white precipitate that formed
  2. customwas collected
  3. customdried

Sources & evidence

ORD record
ord-b5f51bd00fd44a7687c4d09ce59fa466
Source dataset
uspto-grants-1985_11
Patent number
US04551529

Reaction notes

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