HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl (1H-imidazol-yl)hexanoate → (1H-imidazol-1-yl)hexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl (1H-imidazol-yl)hexanoate | HCID 86740497 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | (1H-imidazol-1-yl)hexanoic acid | HCID 20260582 | 82.5% |
Reaction Steps
A solution of 45.1 g of benzyl (1H-imidazol-1-yl)hexanoate in 200 ml of isopropanol was hydrogenated over 10% palladium on carbon. Filtration and evaporation of the solvent gave 24.9 g (80%) of (1H-imidazol-1-yl)hexanoic acid, mp 135°-137° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04551460 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-45eed90e67c24929b2f1de893be3d1e9 |
| Source note | uspto-grants-1985_11 |