HCID 20260583, compound → 6-(Thiophen-3-yl)hexan-1-ol

Participants

Reaction Steps

3-Thiophenehexanol was prepared by reduction of 8.4 g of 6-(3-thiophenyl)-5-hexyn-1-ol, in 100 ml of ethanol over 1.0 g of 10% palladium/carbon at atmospheric pressure. After 8 hours a second catalyst loading was added and the reduction continued over night. The residue obtained after filtration and evaporation of the solvent was evaporatively distilled to give 6.9 g (80%) of 3-thiophenehexanol, bp 135°-147° C./0.2 mm.

Provenance & Evidence