Nitric Acid → HCID 13535752, compound

Participants

Reaction Steps

Into a mixed solution of 8 g of fuming nitric acid and 24 g of acetic anhydride, kept at a temperature of -5° to 10° C., was added dropwise 6 g of (S)-4-hydroxy-3-methyl-2-(2-propenyl)-2-cyclopenten-1-one ([α]D23 : +10.3° (C=1.17, in chloroform), (R)-isomer/(S)-isomer=15.7/84.3). Thereafter, with the same operations as in Example 1, 7.56 g of crude (S)-3-methyl-4-nitroxy-2-(2-propenyl)-2-cyclopenten-1-one was obtained.

Provenance & Evidence