dimethoxytetrahydrofurane → 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-4-oxo-7-(1H-pyrrol-1-yl)-

Participants

Reaction Steps

0.3 Gram of 7-amino-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is suspended in 10 ml of acetic acid, 0.17 gram of dimethoxytetrahydrofuran is added and the mixture is heated until the solid has dissolved. The mixture is filtered, and water is added to the filtrate until it becomes turbid. The filtrate is allowed to cool, and the precipitate obtained is filtered off and washed with ethanol. 0.12 gram of a solid is obtained, of melting point 235°-238° C.

Provenance & Evidence