Allyl bromide → HCID 20240740, compound

Participants

Reaction Steps

A solution of 51 g of N-[2-methyl-3-(o-methyl-phenyl)-propyl]-pyrrolidine and 58 g of allyl bromide in 200 ml of ethyl acetate is refluxed for 5 hours. The product precipitates as a resin. After the ethyl acetate has been decanted, the crude product is triturated several times with ethyl acetate. Supernatant solvent is decanted. Finally, the product is triturated with n-pentane and the solvent decanted. The oil which remains is freed from solvent residues in a rotary evaporator. There remains 60 g of N-allyl-N-[2-methyl-3-(o-methyl-phenyl)-propyl]-pyrrolidinium bromide as a brown resin.

Provenance & Evidence