N-((Phenylmethoxy)carbonyl)-L-alanyl-L-alanine → HCID 13750000, compound

Participants

Reaction Conditions

Reaction Steps

11 grams of N,N-dicyclohexylcarbodiimide was added to a solution of 14.7 grams of benzyloxycarbonylalanyl alanine in 100 ml of dimethylformamide and 7.6 g of proline ethylamine (prepared from the corresponding benzyloxycarbonyl derivative) cooled to -5 degrees C. and the reaction mixture treated by conventional techniques. 10.6 g of product having a melting point of 139 to 140 degrees C. was obtained. [α]D20 -46.5 degrees (c 0.3; dimethylformamide).

Provenance & Evidence