反应详情

A solution of α-hydroxyethylphosphinic acid (5.5 g) and benzyl alcohol (2.26 g) in benzene (50 ml) was heated for 8 hours with removal of water through a Dean-Stark apparatus. After cooling, the reaction mixture was washed with water, dried over magnesium sulfate and concentrated in vacuo to give 3.65 g (91.2%) of benzyl α-hydroxyethylphosphinate (Compound No. 36).

1. temperatureAfter cooling
2. washthe reaction mixture was washed with water
3. dry with materialdried over magnesium sulfate
4. concentrationconcentrated in vacuo