HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-butoxycarbonyl)glycine → HCID 20258244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-butoxycarbonyl)glycine | HCID 78288 | — |
| Reactant | 2-(2-Amino-phenyl)-benzo[d][1,3]oxazin-4-one | HCID 838395 | — |
| Product | HCID 20258244 | HCID 20258244 | — |
Reaction Steps
Using identical reaction conditions as described for the synthesis of the compounds of formula VII of Scheme 2 above, 480 mg (2.0 mmole) of 2-(2-aminophenyl)-3,1-benzoxazin-4-one was reacted with 525 mg (3.0 mmole) of tert-butyloxycarbonylglycine to give 170 mg of the chromatographically-homogeneous tilted compound in 60% overall yield after three cycles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04554272 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-246ab69e470f453ba6ac0a497e68561e |
| Source note | uspto-grants-1985_11 |