Boron tribromide → HCID 135666746, compound

Participants

Reaction Steps

A mixture of 1.83 g (0.00629 m) of 4-methoxy-7-[2-(N,N-di-n-propylamino)ethyl]-1,3-benzimidazol-2-one in 100 ml of methylene chloride was cooled to -30° while 17.5 ml of 1M boron tribromide in methylene chloride was added dropwise. After standing at room temperature for 4 hours, the mixture yielded an oil which solidified. The residue was triturated with methanol, then recrystallized from isopropanol to give 1.94 g (86%) of 4-hydroxy-7-[2-(N,N-di-n-propylamino)ethyl]-1,3-benzimidazol-2-one hydrobromide; 240°-242°.

Provenance & Evidence