Nitric Acid → HCID 13343746, compound

Participants

Reaction Steps

18.4 g of 2,2-dimethyl-5-acetamino-1,3-benzodioxole were nitrated at 15°-25° C. in 90 ml of glacial acetic acid by the dropwise addition of 9.5 ml of nitric acid (d=1.4) in 30 ml of glacial acetic acid. After stirring at room temperature for 3 hours, the suspension was poured into ice/water and the crystals were removed by filtration under suction. These were made into a paste with methanol and again suction filtered. There were obtained 22.0 g (98.2% of theory) of 2,2-dimethyl-5-acetamino-6-nitro-1,3-benzodioxole of melting point 173°-174° C.

Provenance & Evidence