Sodium Methoxide → HCID 54470751, compound

HRID 1583818Notes

Reaction equation

HRID 1583818 reaction equation
C([O:4][C@H:5]1[C@@H:20]([O:21]C(=O)C)[C@H:19]([O:25]C(=O)C)[C@@H:18]([CH2:29][O:30]C(=O)C)[O:17][C@@H:6]1[S:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(=O)C.C[O-].[Na+]>CO>[S:7]([CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C@H:6]1[O:17][C@H:18]([CH2:29][OH:30])[C@@H:19]([OH:25])[C@H:20]([OH:21])[C@@H:5]1[OH:4]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 53709206HCID 53709206, compound

Product 1

HCID 54470751HCID 54470751, compoundYield 92.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Compound 6 (500 mg) is deacetylated with sodium methoxide in methanol to give 7 (300 mg, 92%): m.p. 122°-123° C. (H2O); [α]D27 +185.4±0.9° (C, 1.06, methanol).

Sources & evidence

ORD record
ord-0039ab7bbfb4447f82d87e642c601a8e
Source dataset
uspto-grants-1985_11
Patent number
US04554349

Reaction notes

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