Acetone → HCID 20257392, compound

Participants

Reaction Steps

1.9 g of methyl 2-(1,2-dihydo-2,2-dimethylquinolin-6-yl)propionate (Compound 7) were added to 40 ml of acetone. 2.0 g of potassium carbonate and 2.0 ml of methyl iodide were added to the solution, and the mixture was heated and refluxed for 17 hours. After the mixture was cooled, the mixture was diluted with ether. Then the precipitate was filtered off, and the solvent was distilled off to give 1.9 g of methyl 2-(1,2-dihydro-1,2,2-trimethylquinolin-6-yl)propionate (Compound 16).

Provenance & Evidence