Boron tribromide → HCID 135666744, compound

Participants

Reaction Steps

By the method described in `Advanced Organic Synthesis, Methods and Techniques` Academic Press, p 66 (1971), incorporated herein by reference, 2.0 g (0.0088 mole) of 3-chloro-(4-methoxy-phenyl)-1,2,5-thiadiazole (prepared in manner of Example 2) was reacted with 11.0 g (0.044 mole) of boron tribromide in 60 ml of methylene chloride to produce 1.63 g of 3-chloro-4-(4-hydroxyphenyl)-1,2,5-thiadiazole (m.p. 135°-136.5° C.).

Provenance & Evidence