HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-bromo-2-(4-chlorophenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Bromine | HCID 24408 | — |
| Product | Ethyl 2-bromo-2-(4-chlorophenyl)acetate | HCID 228840 | — |
Reaction Steps
By the method of E. Schwenk and D. Papa, J. A. C. S. 70, 3626 (1948), incorporated herein by reference, 86.8 g (0.509 mole) of p-chlorophenylacetic acid was treated with 100 ml of thionyl chloride. Subsequent reaction with 83.2 g (0.52 mole) of bromine followed by 100 ml of ethanol produced 78.9 g of ethyl alphabromo-(4-chlorophenyl)acetate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04555521 |
| Source dataset | uspto-grants-1985_11 |
| ORD ID | ord-4caa30742950480880aa154bff8131dd |
| Source note | uspto-grants-1985_11 |