Imidazole → 3-(4-Methyl-1H-imidazol-1-yl)propan-1-amine

HRID 1583985Notes

Reaction equation

HRID 1583985 reaction equation
N1C=CN=C1.CC1N(CCCN)C=CN=1.C(C1N(CCCN)C=CN=1)C.C[C:28]1[N:29]([CH2:34][CH2:35][CH2:36][NH2:37])[CH:30]=[C:31]([CH3:33])[N:32]=1.C1(C2N(CCCN)C=CN=2)C=CC=CC=1.C1(C2N=CN(CCCN)C=2)C=CC=CC=1>>[CH3:33][C:31]1[N:32]=[CH:28][N:29]([CH2:34][CH2:35][CH2:36][NH2:37])[CH:30]=1

Participants

7

Reactant 6

HCID 795ImidazoleHCID 31521053-(2-methyl-1H-imidazol-1-yl)propan-1-amineHCID 64841343-(2-Ethyl-1H-imidazol-1-yl)-1-propanamineHCID 135889102,4-dimethyl-1H-imidazole-1-propanamineHCID 135889112-phenyl-1H-imidazole-1-propanamineHCID 135889123-(4-Phenyl-1H-imidazol-1-yl)propan-1-amine

Product 1

HCID 150349543-(4-Methyl-1H-imidazol-1-yl)propan-1-amine

Procedure

By substituting the appropriate imidazole starting material in the above procedure, the following intermediates were prepared: 2-methyl-1H-imidazole-1-propanamine; 2-ethyl-1H-imidazole-1-propanamine; 2,4-dimethyl-1H-imidazole-1-propanamine; 2-phenyl-1H-imidazole-1-propanamine; and 4-phenyl-1H-imidazole-1-propanamine.

Workup

  1. customthe following intermediates were prepared

Sources & evidence

ORD record
ord-d0e2f899fc764fea92c01ad6dca769d1
Source dataset
uspto-grants-1985_11
Patent number
US04555519

Reaction notes

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