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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1583992Generated: October 31, 2026

6-Chloronicotinic acid → 6-Chloro-N-[3-(1H-imidazol-1-yl)-2-methylpropyl]-3-pyridinecarboxamide

https://huagongshe.com/reaction/1583992

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloronicotinic acidHCID 79222—
Reactant3-(1H-Imidazol-1-yl)-2-methylpropan-1-amineHCID 13952859—
Product6-Chloro-N-[3-(1H-imidazol-1-yl)-2-methylpropyl]-3-pyridinecarboxamideHCID 20257578—

Reaction Steps

When 6-chloronicotinic acid was reacted with 3-(1H-imidazol-1-yl)-2-methylpropanamine by the procedure of Example 20, the compound of the Example was obtained, mp 102°-104° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04555519
Source datasetuspto-grants-1985_11
ORD IDord-2f00c09a639d4026926c57303137cb5e
Source noteuspto-grants-1985_11