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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1583994Generated: November 3, 2026

1,1'-Carbonyldiimidazole → 6-Chloro-N-[3-(2,4-dimethyl-1H-imidazol-1-yl)propyl]-3-pyridinecarboxamide

https://huagongshe.com/reaction/1583994

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant6-Chloronicotinic acidHCID 79222—
Reactant2,4-dimethyl-1H-imidazole-1-propanamineHCID 13588910—
Product6-Chloro-N-[3-(2,4-dimethyl-1H-imidazol-1-yl)propyl]-3-pyridinecarboxamideHCID 20257595—

Reaction Steps

When 2,4-dimethyl-1H-imidazole-1-propanamine is treated with a mixture of 6-chloronicotinic acid and 1,1'-carbonyldiimidazole by the procedure of Example 30 the compound of the Example is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04555519
Source datasetuspto-grants-1985_11
ORD IDord-b38e082679284f15be954575a558a982
Source noteuspto-grants-1985_11